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How to replace the toner cartridges for the AcuLaser CX21N/CX21NF?


    Lifetime Part No. Pictures
    High capacity Toner cartridge (Yellow)** C13S050316
    High capacity Toner cartridge (Magenta)** C13S050317
    High capacity Toner cartridge (Cyan)** C13S050318
    High capacity Toner cartridge (Black)** C13S050319
    **High capacity = up to 4000 pages.


    Notes Icon Note:

    These cartridges are not compatible with the previous Aculaser models, the C1100(N) and CX11N(F). Click on the model names for instructions.


    Before starting, please note the handling precautions below.

    Caution Icon Caution:
    • Handle cartridges with care. Toner is free to spill out of a toner cartridge when it is in the locked position.

    • Be aware that during removal or cleaning, toner powder could get onto your hands, clothing or work surfaces.

    • Prepare a clean, level work surface before starting, and put down paper if required.

    • You may need a soft, dry, lint-free cloth with which to clean the cartridges.

    • Do not touch the toner. Keep the toner away from your eyes. If toner gets on your skin or clothes, wash it off with soap and water immediately.

    • If toner is spilled, use a broom and dustpan or a damp cloth with soap and water to clean it up. Because the fine particles can cause a fire or explosion if they come into contact with a spark, do not use a vacuum cleaner.
    Caution Icon Caution:

    We recommend using genuine Epson toner cartridges. Using non-genuine consumable products may affect the operation of your printer. Epson are not liable for any damages or problems arising from the use of consumable products not manufactured or approved by Epson.

    The toner cartridge has reached the end of its service life.

      The printer stops printing and displays the following message on the LCD panel or the window of EPSON Status Monitor:


      LCD Panel Message Description
      Replace Toner uuuu* The toner cartridge for the indicated colour is empty.
      *The letters C, M, Y, or K appear in this position, indicating the colour of the toner to be replaced.


      If the "Replace Toner uuuu" message is displayed, follow the procedure below to change the toner cartridge:

      1. Power the printer on.

      2. Check the colour of the toner cartridge to be replaced in the LCD panel, and then open Cover A.

        Cover A open


      3. Push up the right lever to unlock the toner cartridge.

        Unlock the toner cartridge


      4. Remove the toner cartridge from the printer.

        Remove the cartridge


      5. Take the new toner cartridge out of its packaging and gently shake the toner cartridge as shown below.

        Gently shake the new cartridge


      6. Hold the tag and gently pull the toner seal upward and remove it.

        Remove the cartridge seal


      7. Insert the cartridge all the way until it stops securely with the arrow mark on the top of the toner cartridge facing toward Cover A.

        Insert the cartridge


        Notes Icon Note:

        Hold the cartridge in the middle as shown in the picture. Push it gently all the way through the rails. Make sure both sides of the cartridge are inserted at the same time. Keep some pressure in the middle of cartridge until you hear a 'click'.


      8. Push down the right lever to lock the toner cartridge.

        Lock the cartridge


      9. Close Cover A.

        Close Cover A


      10. Check the display on the LCD panel. When another toner cartridge needs to be replaced, an error message is displayed. Repeat the steps above to replace the cartridge.

      Notes Icon Note:

      To see a video on setting up your toner cartridges for the first time, click here.

    You want to replace a toner cartridge before the end of its service life.

    LCD Panel Message Description
    uuuu Toner Low* The toner cartridge for the indicated colour is nearly empty.
    *C, M, Y, and/or K are indicated for the colour of the toner to be replaced. For example, the message Y Toner Low means that the amount of remaining toner in the yellow toner cartridge is low.


    1. Make sure that Ready or Sleep is displayed on the LCD panel.

    2. Select Change Toner X (the letters C, M, Y, or K appear in place of X, indicating the colours Cyan, Magenta, Yellow, and Black) in the Reset Menu on the control panel.

    3. While the cartridge X you selected above moves to the cartridge replacement position, "Please Wait" appears on the LCD panel.

    4. "Replace Toner X" appears in the LCD panel when the cartridge to be replaced reaches the cartridge replacement position.

    5. Follow the procedure of Step 2 to change the toner cartridge.

    Notes Icon Note:

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